1 Acetyl 4 (4 hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen.
Its multi step preparation using bis (2 chloroethyl)amine hydrochloride and p aminophenol as starting materials has been reported.
Application
1 Acetyl 4 (4 hydroxyphenyl)piperazine may be used in the preparation of 1 acetyl 4 (4 octadecyloxyphenyl)piperazine.
It may also be used in the multi step synthesis of ketoconazole,
Its 1,2,4 triazole and thiazole analogs.